Patrick Marcellin Selected Research

Ribavirin (Virazole)

10/2020	Sofosbuvir-Daclatasvir is suboptimal in patients with genotype 2 chronic hepatitis C infection: real-life experience from the HEPATHER ANRS CO22 cohort.
4/2019	Clinical outcomes in patients with chronic hepatitis C after direct-acting antiviral treatment: a prospective cohort study.
4/2019	Safety and efficacy of the combination simeprevir-sofosbuvir in HCV genotype 1- and 4-mono-infected patients from the French ANRS CO22 hepather cohort.
1/2017	Safety and efficacy of daclatasvir-sofosbuvir in HCV genotype 1-mono-infected patients.
1/2017	Efficacy and safety of sofosbuvir-based therapies in patients with advanced liver disease in a real-life cohort.
1/2016	A randomized, controlled study of peginterferon lambda-1a/ribavirin ± daclatasvir for hepatitis C virus genotype 2 or 3.
8/2015	Improvement of health-related quality of life and work productivity in chronic hepatitis C patients with early and advanced fibrosis treated with ledipasvir and sofosbuvir.
7/2015	Safety and tolerability of ledipasvir/sofosbuvir with and without ribavirin in patients with chronic hepatitis C virus genotype 1 infection: Analysis of phase III ION trials.
7/2015	Ledipasvir and sofosbuvir in patients with genotype 1 hepatitis C virus infection and compensated cirrhosis: An integrated safety and efficacy analysis.
6/2015	Ombitasvir plus paritaprevir plus ritonavir with or without ribavirin in treatment-naive and treatment-experienced patients with genotype 4 chronic hepatitis C virus infection (PEARL-I): a randomised, open-label trial.

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Patrick Marcellin Research Topics

Disease

86	Chronic Hepatitis B 01/2022 - 01/2002
81	Infections 01/2021 - 08/2002
78	Fibrosis (Cirrhosis) 01/2022 - 01/2002
65	Chronic Hepatitis C 10/2020 - 01/2002
31	Hepatitis C 01/2022 - 01/2002
16	Liver Cirrhosis (Hepatic Cirrhosis) 01/2022 - 01/2005
15	Liver Diseases (Liver Disease) 01/2021 - 01/2002
14	Hepatocellular Carcinoma (Hepatoma) 01/2020 - 08/2006
13	Hepatitis B 01/2020 - 08/2002
10	Virus Diseases (Viral Diseases) 06/2015 - 06/2004
8	Viremia 01/2021 - 06/2004
6	Chronic Hepatitis (Chronic Active Hepatitis) 01/2021 - 09/2006
6	Coinfection 01/2019 - 07/2004
6	Insulin Resistance 10/2012 - 08/2007
5	Hepatitis 01/2022 - 04/2003
5	Persistent Infection 01/2021 - 06/2004
5	Inflammation (Inflammations) 11/2016 - 01/2002
3	Headache (Headaches) 10/2020 - 09/2004
3	Fatigue 10/2020 - 09/2004
3	End Stage Liver Disease 01/2020 - 11/2006
3	Anemia 06/2011 - 01/2010
2	Ascites 01/2022 - 05/2010
2	Disease Progression 01/2022 - 07/2003
2	Hemorrhage 01/2022 - 05/2010
2	Hypertension (High Blood Pressure) 04/2019 - 01/2018
2	Diabetes Mellitus 01/2018 - 08/2007
2	Chronic Disease (Chronic Diseases) 08/2015 - 04/2011
2	Neutropenia 02/2013 - 01/2012
2	Body Weight (Weight, Body) 08/2011 - 06/2004
2	Fatty Liver 11/2010 - 06/2006
2	Vasculitis (Vasculitides) 02/2008 - 06/2006
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 02/2008 - 08/2007
2	Liver Failure 06/2005 - 07/2004

Drug/Important Bio-Agent (IBA)

73	Ribavirin (Virazole)FDA LinkGeneric 10/2020 - 01/2002
65	InterferonsIBA 01/2021 - 01/2002
46	Antiviral Agents (Antivirals)IBA 04/2019 - 02/2003
45	Hepatitis B e AntigensIBA 01/2021 - 01/2002
29	Hepatitis B Surface Antigens (HBsAg)FDA Link 01/2020 - 06/2005
27	DNA (Deoxyribonucleic Acid)IBA 04/2022 - 02/2003
27	Tenofovir (Viread)FDA Link 10/2019 - 03/2007
20	RNA (Ribonucleic Acid)IBA 01/2022 - 10/2002
18	peginterferon alfa-2a (Pegasys)FDA Link 01/2020 - 02/2004
18	Alanine Transaminase (SGPT)IBA 07/2017 - 10/2002
14	Lamivudine (Epivir)FDA Link 01/2012 - 01/2002
13	Protease Inhibitors (Protease Inhibitor)IBA 04/2019 - 12/2010
13	adefovir dipivoxil (Hepsera)FDA Link 03/2011 - 02/2003
11	NucleosidesIBA 02/2014 - 07/2004
11	Interferon-alpha (Interferon Alfa)IBA 11/2007 - 01/2002
10	NucleotidesIBA 01/2020 - 02/2003
8	SofosbuvirIBA 10/2020 - 02/2014
8	SimeprevirIBA 04/2019 - 01/2011
8	telaprevirIBA 01/2015 - 02/2011
8	N- (3- amino- 1- (cyclobutylmethyl)- 2,3- dioxopropyl)- 3- (2- ((((1,1- dimethylethyl)amino)carbonyl)amino)- 3,3- dimethyl- 1- oxobutyl)- 6,6- dimethyl- 3- azabicyclo(3.1.0)hexan- 2- carboxamideIBA 01/2015 - 03/2011
8	adefovirIBA 04/2014 - 12/2005
7	AntigensIBA 10/2018 - 07/2004
6	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 05/2016 - 01/2002
6	Pharmaceutical PreparationsIBA 02/2014 - 01/2002
5	daclatasvirIBA 10/2020 - 02/2014
5	entecavir FDA Link 09/2016 - 03/2007
5	danoprevirIBA 10/2013 - 12/2010
5	CytokinesIBA 01/2012 - 01/2002
4	Biomarkers (Surrogate Marker)IBA 01/2022 - 11/2002
4	sofosbuvir drug combination ledipasvirIBA 08/2015 - 05/2014
4	Telbivudine FDA Link 01/2015 - 03/2007
4	Proteins (Proteins, Gene)FDA Link 10/2010 - 06/2006
3	BilirubinIBA 01/2022 - 05/2016
3	tenofovir alafenamideIBA 10/2018 - 11/2016
3	MicroRNAs (MicroRNA)IBA 10/2016 - 11/2012
3	F 4 (F-4)IBA 11/2015 - 02/2006
3	ledipasvirIBA 08/2015 - 05/2014
3	Interferon alpha-2 (Roferon-A)FDA Link 08/2014 - 02/2004
3	Emtricitabine (Emtriva)FDA Link 04/2014 - 03/2007
3	Erythropoietin FDA Link 09/2013 - 08/2007
3	Messenger RNA (mRNA)IBA 10/2010 - 02/2005
3	clevudineIBA 12/2008 - 07/2004
3	Transforming Growth Factor beta (TGF-beta)IBA 03/2007 - 01/2002
2	Viral RNAIBA 01/2021 - 06/2011
2	bulevirtideIBA 01/2021 - 01/2021
2	Viral DNAIBA 07/2017 - 11/2010
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 04/2016 - 02/2006
2	asunaprevirIBA 11/2014 - 02/2014
2	faldaprevirIBA 02/2014 - 02/2014
2	InterleukinsIBA 02/2014 - 03/2012
2	Circular DNAIBA 02/2014 - 06/2004
2	Transaminases (Aminotransferases)IBA 12/2013 - 11/2002
2	gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)IBA 08/2011 - 06/2006
2	lipoarabinomannan (LAM)IBA 05/2010 - 03/2009
2	Interferon-alpha2bIBA 01/2010 - 09/2006
2	Interleukin-8 (Interleukin 8)IBA 09/2008 - 03/2007
2	CryoglobulinsIBA 02/2008 - 06/2006
2	AntibodiesIBA 11/2007 - 10/2007
2	Triglycerides (Triacylglycerol)IBA 08/2007 - 08/2007
2	peginterferon alfa-2b (Pegintron)FDA Link 04/2007 - 06/2004

Therapy/Procedure

92	Therapeutics 01/2021 - 01/2002
11	Liver Transplantation 04/2019 - 08/2002
5	Transplantation 01/2018 - 08/2002
4	Aftercare (After-Treatment) 01/2021 - 09/2008
4	Duration of Therapy 02/2014 - 03/2004
4	Retreatment 06/2012 - 04/2007
2	Subcutaneous Injections 01/2021 - 08/2014